Transanal Irrigation With a Validated Pediatric Neurogenic Bowel Dysfunction Scoring System
For a study, researchers sought to assess the effectiveness of transanal irrigation (TAI) in pediatric patients with neurogenic bowel dysfunction (NBD) who had not previously received catheter-based TAI using the Peristeen device (Coloplast). The prospective enrollment of NBD patients who were dissatisfied with their bowel regimen or who were not on a bowel regimen in situ was assessed using the neurogenic bowel dysfunction score (NBDS) prior to starting Peristeen medication (time point 0). NBDS scores were assessed twice: first during the first 6 months (time 1) after starting Peristeen and again after more than 6 months (time 2).
ABOUT 104 people with NBD were enrolled in the study over a 26-month period. The mean age was 10.6 years and 4.7 months (range: 3-18 years). The NBDS on Time 1 was on average 14 points lower than the original score. Time 2 showed a similar trend, with an average decrease of 13 points from the original score. At Time 1, there was a statistically significant drop of 14 points, P < 0.001, which was maintained at Time 2 with a statistically significant drop in scores from the start of 13 points, P < 0.001. Peristeen improved patient satisfaction and quality of life at both Time 1 and Time 2.
Peristeen appears to improve quality of life in pediatric patients with NBD, according to the findings. When young patients with NBD started on Peristeen, their NBDS improved significantly. Lower scores were achieved on both Time 1 and Time 2, indicating that their overall NBP had improved.