Pediatric Titration Sleep Studies and the Effect on Adherence to Therapy

For a study, the researchers sought to see how often polysomnography (PSG) titration leads to changes in empirically prescribed positive airway pressure (PAP) and how adherence was affected before and after PSG titration. Between 2008 and 2012, a retrospective review of medical records was performed for children diagnosed with obstructive sleep apnea (OSA), prescribed PAP and a titration of PSG. Researchers looked at demographic information, device type, pressure settings, and adherence downloads. Adherence was measured before and after titration in general, and those who had therapeutic modifications after titration were compared with those who did not. A total of 121 people took part in the study. At the time of the diagnostic PSG, the median age was 11 years (interquartile range [IQR] 8-14). APAP was initially prescribed to most patients (106 or 88%). The median interval between initial and follow-up PSG was 6.4 months (IQR 4.4-10.1). After titration, most patients (94.78%) had therapeutic adjustments. In general, the percentage of people who slept more than 4 hours per night did not increase significantly after titration (P=.47). The difference in adherence between individuals who had therapy improvements and those who did not (P=.26) was not statistically significant. In the majority of children, titration studies resulted in therapeutic adjustments. Adherence to treatment did not improve after the PSG titration. Adherence to treatment did not improve as a result of the changes. PSGs for titration can help to improve empirically prescribed settings.

Source:rc.rcjournal.com/content/67/464

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